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Ixekizumab (CAT#: TAB-217)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL17RA Recombinant Antibody TAB-217 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IL17RA. Ixekizumab is a humanized monoclonal antibody used in the treatment of autoimmune diseases.
  • Target
  • IL17RA
  • Type
  • IgG4 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, IP, IF, FuncS, FC, Neut, ELISA and most other immunological methods.
  • CAS
  • 1143503-69-8
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G4, anti-(human interleukin 17A) (human monoclonal LY2439821 γ4-chain), disulfide with human monoclonal LY2439821 kappa-chain, dimer
  • Predicted N terminal
  • H chain: QVQLVQS; L chain: DIVMTQT
  • Molecular Weight
  • 146200
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Interleukin 17 Receptor Alpha is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
  • Function
  • interleukin-17 receptor activity; receptor activity;
  • Synonyms
  • IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262;

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